Yea, I see what you mean now…may I ask why the manifold? Just run a spiral line the width of the part on one end and sprial vac on the other…easier that way KD, plus it is a controlled flow in one direction. Your issue with the dry spots was based on saturation, we know you had good vacuum, no holes (even the one mentioned won’t cause that), a slow enough infusion, your lay-up was not an issue, but the resin did not saturate through the laminate skin layers.
It is plausible the manifold method allowed the resin to run quick through the center of the part, only to cause traffic for the subsequent feed of the resin so to speak. The key is maintain an equal and always consistent feed rate that saturates the laminate skins (fabric) at the same rate from the beginning to the end.
On your next one, try just running vacuum from one side, feed line on the other, lay-up as usual, flow media from one side to the other on the entire part (minus the flange), pinch your line 1/4 the way of width and see if it results in a better infusion.