The “K” as you already represents the # of filaments in the yarn. The weight represents the areal weight of one square yard of fabric. So, the 12K spread tow only weight 5 ounce per square yard while the 12 twill weighs 20 ounces per square yard. The 12 spread tow in thin while the 12K twill is much thicker.
The major advantage to spread tow fabric is a reduction in crimp. Crimp is the waviness of the yarn as it goes up and over the crossing yarns. Crimp has two negatives: 1) It causes the fibers to be out of plane with loading axis. Think of it like a spring. When the fibers are put under tension the crimp tries to straighten which stresses the resin and reduces tensile stiffness of the laminate. Under compression the crimp promote micro-buckling. 2) The crimp creates more space between the fibers at the crossing yarn junctions that needs to be filled with resin. This increases the amount of resin need for a given amount of fiber.
Unidirectional fabrics and bi-directional mats have very little crimp. For this reason they are typically used in in the most demanding applications where higher fiber volume fractions and performance are needed. 1 atmosphere bagging/infusion can get a Vf 60% with UD materials. The only time woven materials are used is when “bling” is desired, speed of processing is required, or the available UD materials in multiple layers can’t meet the weight requirements.
Spread tow is very handy in very light structures where multiple layers of UD material can’t meet the weight requirements. It comes is very light arrangements and has fiber in two directions. It’s the next best thing after UD materials. It has low crimp but is usually psychotically expensive. You can get Vf of 55% or better with one atmosphere. It will infuse very nicely. Personally, I wouldn’t consider using the stuff unless the structure requires very thin and very light skins/walls.
The 12K 20 ounce twill has a very high degree of crimp. The yarns have go up and over rather large bundles. It’s typically used to speed up manufacturing and reduce cost. In general, multiple layers of lighter woven fabric is stronger, more durable, and yields a more favorable fiber volume fraction (Vf) than heavy woven fabrics. 4 layers of 3K will cost you $100 or more per yard while 1 layer of 12K twill is only $80 (often less), and less labor to handle. The advantage is with multiple layers you can very the orientations to maximize its properties while the one heavy layer to 12K will only allow fiber is two directions. It’s all compromises.
So, to answer your question :): Multiple layers of the 5 ounce 12K spread tow will perform better than the 12K twill 20 ounce fabric…but it will cost you a lot more money.