Bladder split-mold vs 2-half vacuum bag and joining

So I’m looking to build a bike frame whose tubes aren’t necessarily round, but they should have side angles positive enough for removal from a mold. My main concern is this: is there a significant strength loss from creating something like this from 2 halves and then joining them down the middle? Obviously the method of joining would be important, but I just want to make sure that it wont catastrophically fail due to a flawed assumption on my part and it will be just as strong in the proper directions.

Any input would be greatly appreciated! Bladder split-molding is an option, but it would be fairly complicated and expensive on a per-try basis, so if it’s possible, I’d much prefer doing it in two halves, split vertically through the center.

Sorry I don’t have a picture of the actual frame, everything has been molded by hand, but it’s extremely similar to this Audi electric bike frame and is just for personal use.
http://www.electricbikee.com/wp-content/uploads/2012/09/audi-11.jpg

I think it would help if you described what materials your using, are you leaving the frame hollow or will you use a core material? Resin system ?

If the seam between the two halves is constructed properly then the seam will not be the weak point. A co-cured seam is best.

Thanks for the replies!

So far, the plan is to use 2x2 twill, probably 3k, and some epoxy that my brother bought when he worked with fiberglass for a school project a little while ago, I don’t really know the specifics on that, though. I was going to wet lay-up into a female mold and then vacuum bag it in two halves, split vertically from front to back.

What did you mean by co-curing?

Co-cured means that the seam and the layup are all cured together during one curing session.